ModelRefs / Clinical Trial Matching — Canonical Workflow
Clinical Trial Matching — Canonical Workflow
Clinical Trial Matching: provisional AI workflow implementation reference with candidate models, providers, tools, and architecture.
Overview
Screen authorized patient data against versioned trial criteria to prepare candidate matches and missing-data flags for coordinator and investigator review; eligibility and enrollment are not determined. Healthcare deployment requires organization- and jurisdiction-specific review of privacy, security, access, retention, and applicable regulatory obligations. Outputs remain provisional and require qualified human review; no clinical autonomy or compliance claim is implied. Validate PHI flows, source traceability, model and prompt versions, reviewer actions, rollback, and incident handling before clinical use.
Implementation profile
| Category | llms |
|---|---|
| Implementation maturity | enterprise |
| Primary use cases | rag, extraction |
| Deployment options | managed-api, hybrid |
| Architectures | serverless-api, managed-container, hybrid-private-cloud |
What this evidence does not establish
- No disease area, trial inventory, site geography, patient schema, terminology map, consent basis, coordinator process, or acceptance threshold is registered.
- No measured criterion accuracy, candidate recall, false-match rate, missed-match rate, review burden, or enrollment outcome is attached.
Candidate models with published references
- BGE-M3
- GPT-5
- GPT-5 Mini
- Claude Sonnet 4.5
- Claude Opus 4
- Gemini 3 Pro
- Llama 4 Scout
- DeepSeek R1
- Mistral Large 2
- Command R+
- o3
- o4 Mini
Coverage means the model is a candidate worth evaluating for this workflow, not a ranking or a recommendation. Models whose reference pages are still in review are omitted.
Benchmarks relevant to this workflow
- GPQA Diamond — Graduate-level Google-Proof Q&A in physics, chemistry, and biology.
- MMLU-Pro — Harder MMLU successor with 10-option questions and reduced contamination.
- MMLU — Massive Multitask Language Understanding — 57 academic and professional subjects.
These are the benchmarks whose task shape bears on this workflow. Each one only describes its own protocol and date, so confirm the harness matches your workload before treating a score as evidence.
Continue your research
Use these connected ModelRefs sections to compare alternatives, inspect implementation paths, and review the evidence and governance boundaries relevant to Clinical Trial Matching — Canonical Workflow.